Antiviral screen identifies EV71 inhibitors and reveals camptothecin-target, DNA topoisomerase 1 as a novel EV71 host factor

• Main Authors: Wu, KX, Chu, JJH
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Elsevier BV 2020
• Subjects: Animals; Antibodies, Monoclonal; Antibodies, Viral; Antiviral Agents; Biological Products; Camptothecin; Cell Line; Cell Survival; DNA Topoisomerases, Type I; Drug Evaluation, Preclinical; Enterovirus; Enterovirus A, Human; Enterovirus Infections; Gene Knockdown Techniques; Goats; Luciferases; Mice; Microscopy, Confocal; RNA, Small Interfering; Rabbits; Replicon; Viral Proteins; Virus Replication
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173154
• Institution: National University of Singapore

10.1016/j.antiviral.2017.04.008