A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

• Main Authors: Luukkainen A., Puan K.J., Yusof N., Lee B., Tan K.S., Liu J., Yan Y., Toppila-Salmi S., Renkonen R., Chow V.T., Rotzschke O., Wang Y.
• Other Authors: OTOLARYNGOLOGY
• Format: Article
• Published: 2020
• Subjects: chemokine; cytokine; interferon; cell culture; coculture; human; immunology; influenza; Influenza A virus (H3N2); innate immunity; male; middle aged; monocyte; mononuclear cell; natural killer cell; nose mucosa; procedures; stem cell; T lymphocyte; virology; Cells, Cultured; Chemokines; Coculture Techniques; Cytokines; Humans; Immunity, Innate; Influenza A Virus, H3N2 Subtype; Influenza, Human; Interferons; Killer Cells, Natural; Leukocytes, Mononuclear; Male; Middle Aged; Monocytes; Nasal Mucosa; Stem Cells; T-Lymphocytes
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173747
• Institution: National University of Singapore

10.3389/fimmu.2018.02514