Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells

• Main Authors: Pandey, V, Zhang, M, Chong, Q.-Y, You, M, Raquib, A.R, Pandey, A.K, Liu, D.-X, Liu, L, Ma, L, Jha, S, Wu, Z.-S, Zhu, T, Lobie, P.E
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2020
• Subjects: caspase 7; cyclin D1; cyclin dependent kinase 2; cyclin dependent kinase 4; cyclin dependent kinase inhibitor 1B; estrogen receptor alpha; Ki 67 antigen; messenger RNA; protein bcl 2; protein c jun; protein p53; scatter factor receptor; STAT3 protein; tamoxifen; transcription factor Snail; transcription factor Sp1; trefoil factor 3; Twist related protein 1; uvomorulin; adult; AN3-CA cell line; anchorage independent growth; animal cell; animal experiment; animal model; animal tissue; apoptosis; Article; BCL2 gene; BCL2L1 gene; carcinogenicity; CASP7 gene; CCND1 gene; CCNE1 gene; CDK2 gene; CDK4 gene; CDKN1B gene; cell cycle progression; cell cycle S phase; cell migration; cell proliferation; cell survival; cell viability; clinical article; cohort analysis; controlled study; DNA methylation; ECC-1 cell line; endometrial carcinoma cell line; endometrium; endometrium carcinoma; female; FN1 gene; gene expression regulation; human; human cell; human tissue; marker gene; mouse; nonhuman; OCLN gene; promoter region; protein expression; RL95-2 cell line; TFF3 gene; transcription initiation; tumor growth; tumor invasion; tumor suppressor gene; tumor volume; tumor xenograft; TWIST1 gene; upregulation; VIM gene
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173802
• Institution: National University of Singapore

10.18632/oncotarget.20461