PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes

• Main Authors: Endoh, M, Endo, T.A, Shinga, J, Hayashi, K, Farcas, A, Ma, K.-W, Ito, S, Sharif, J, Endoh, T, Onaga, N, Nakayama, M, Ishikura, T, Masui, O, Kessler, B.M, Suda, T, Ohara, O, Okuda, A, Klose, R, Koseki, H
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2020
• Subjects: BMI1 protein; Max protein; melengestrol acetate; peptides and proteins; polycomb group ring finger protein 6; RING finger protein; transcription factor Dp1; transcription factor E2F6; transcription factor YAF2; unclassified drug; WDR5 protein; histone; Pcgf6 protein, mouse; Rnf2 protein, mouse; ubiquitin protein ligase; animal cell; animal tissue; Article; cell differentiation; cell growth; cell viability; controlled study; electroporation; embryo development; embryonic stem cell; gene control; gene expression; gene ontology; gene repression; gene silencing; gene targeting; histology; human; human cell; immunoprecipitation; mouse; nonhuman; protein interaction; reverse transcription polymerase chain reaction; upregulation; Western blotting; animal; gene expression regulation; metabolism; physiology; Animals; Cell Differentiation; Embryonic Stem Cells; Gene Expression Regulation; Gene Silencing; Histones; Mice; Polycomb Repressive Complex 1; Ubiquitin-Protein Ligases
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/173932
• Institution: National University of Singapore

10.7554/eLife.21064