ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferation

• Main Authors: Yuan, Y, Anbalagan, D, Lee, L.H, Samy, R.P, Shanmugam, M.K, Kumar, A.P, Sethi, G, Lobie, P.E, Lim, L.H.K
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2020
• Subjects: annexin; annexin 1; estrogen receptor; immunoglobulin enhancer binding protein; microRNA; microRNA 196a; Myc protein; synaptotagmin I; unclassified drug; lipocortin 1; MIRN196 microRNA, human; MYC protein, human; Article; breast cancer; cancer inhibition; cell proliferation; controlled study; gene expression; human; human cell; in vivo study; MCF 7 cell line; protein function; RNA transcription; tumor growth; animal; Bagg albino mouse; breast tumor; female; gene expression regulation; genetics; MCF-7 cell line; metabolism; nude mouse; pathology; physiological feedback; RNA interference; tumor cell line; tumor volume; xenograft; Animals; Annexin A1; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Feedback, Physiological; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; NF-kappa B; Proto-Oncogene Proteins c-myc; RNA Interference; Transplantation, Heterologous; Tumor Burden
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174092
• Institution: National University of Singapore

10.18632/oncotarget.8875