Efficient differentiation of human embryonic stem cells to arterial and venous endothelial cells under feeder- and serum-free conditions

• Main Authors: Sriram, G, Tan, J.Y, Islam, I, Rufaihah, A.J, Cao, T
• Other Authors: DENTISTRY
• Format: Article
• Published: 2020
• Subjects: bone morphogenetic protein 4; CD31 antigen; CD34 antigen; fibroblast growth factor 2; glycogen synthase kinase 3; transcriptome; vasculotropin; 6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile; pyridine derivative; pyrimidine derivative; vasculotropin A; angiogenesis; animal experiment; animal model; animal tissue; Article; cell differentiation; cell function; cell migration; cell population; controlled study; culture medium; embryonic stem cell; endoderm; endothelial progenitor cell; endothelium cell; human; human cell; in vitro study; in vivo study; mesoderm; microvasculature; mouse; nonhuman; phenotype; priority journal; risk assessment; animal; antagonists and inhibitors; artery; cell lineage; cytology; drug effects; human embryonic stem cell; metabolism; nonobese diabetic mouse; SCID mouse; transplantation; vascular endothelium; xenograft; Animals; Antigens, CD31; Antigens, CD34; Arteries; Bone Morphogenetic Protein 4; Cell Differentiation; Cell Lineage; Endothelial Cells; Endothelium, Vascular; Fibroblast Growth Factor 2; Glycogen Synthase Kinase 3; Human Embryonic Stem Cells; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Pyridines; Pyrimidines; Transplantation, Heterologous; Vascular Endothelial Growth Factor A
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174118
• Institution: National University of Singapore

10.1186/s13287-015-0260-5