Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy

10.1186/s12943-015-0391-4

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Main Authors: Ling L., Tan S.K., Goh T.H., Cheung E., VICTOR NURCOMBE, van Wijnen A.J., Cool S.M.
Other Authors: BIOCHEMISTRY
Format: Article
Published: BioMed Central Ltd. 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/174283
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-1742832024-04-18T07:32:45Z Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy Ling L. Tan S.K. Goh T.H. Cheung E. VICTOR NURCOMBE van Wijnen A.J. Cool S.M. BIOCHEMISTRY ORTHOPAEDIC SURGERY 1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea 3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid antibodies,antisera and immunoglobulins antineoplastic agent fibroblast growth factor receptor 1 heparan sulfate heparin binding protein imb r1 phospholipase C gamma protein p53 unclassified drug antineoplastic agent fibroblast growth factor 2 fibroblast growth factor receptor 1 heparin messenger RNA monoclonal antibody antioxidant assay apoptosis Article cancer survival cell survival controlled study cross reaction down regulation drug protein binding enzyme activation enzyme linked immunosorbent assay human human cell immunohistochemistry methodology proof of concept study protein domain protein targeting quantitative analysis real time polymerase chain reaction sequence homology signal transduction Student t test upregulation Western blotting antagonists and inhibitors biopsy cell proliferation chemistry drug effects gene expression regulation genetics metabolism molecularly targeted therapy Neoplasms pathology protein domain Antibodies, Monoclonal Antineoplastic Agents Apoptosis Biopsy Cell Proliferation Fibroblast Growth Factor 2 Gene Expression Regulation, Neoplastic Heparin Humans Molecular Targeted Therapy Neoplasms Protein Interaction Domains and Motifs Receptor, Fibroblast Growth Factor, Type 1 RNA, Messenger Signal Transduction 10.1186/s12943-015-0391-4 Molecular Cancer 14 1 136 2020-09-04T02:09:47Z 2020-09-04T02:09:47Z 2015 Article Ling L., Tan S.K., Goh T.H., Cheung E., VICTOR NURCOMBE, van Wijnen A.J., Cool S.M. (2015). Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy. Molecular Cancer 14 (1) : 136. ScholarBank@NUS Repository. https://doi.org/10.1186/s12943-015-0391-4 14764598 https://scholarbank.nus.edu.sg/handle/10635/174283 BioMed Central Ltd. Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea
3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid
antibodies,antisera and immunoglobulins
antineoplastic agent
fibroblast growth factor receptor 1
heparan sulfate
heparin binding protein
imb r1
phospholipase C gamma
protein p53
unclassified drug
antineoplastic agent
fibroblast growth factor 2
fibroblast growth factor receptor 1
heparin
messenger RNA
monoclonal antibody
antioxidant assay
apoptosis
Article
cancer survival
cell survival
controlled study
cross reaction
down regulation
drug protein binding
enzyme activation
enzyme linked immunosorbent assay
human
human cell
immunohistochemistry
methodology
proof of concept study
protein domain
protein targeting
quantitative analysis
real time polymerase chain reaction
sequence homology
signal transduction
Student t test
upregulation
Western blotting
antagonists and inhibitors
biopsy
cell proliferation
chemistry
drug effects
gene expression regulation
genetics
metabolism
molecularly targeted therapy
Neoplasms
pathology
protein domain
Antibodies, Monoclonal
Antineoplastic Agents
Apoptosis
Biopsy
Cell Proliferation
Fibroblast Growth Factor 2
Gene Expression Regulation, Neoplastic
Heparin
Humans
Molecular Targeted Therapy
Neoplasms
Protein Interaction Domains and Motifs
Receptor, Fibroblast Growth Factor, Type 1
RNA, Messenger
Signal Transduction
spellingShingle 1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea
3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid
antibodies,antisera and immunoglobulins
antineoplastic agent
fibroblast growth factor receptor 1
heparan sulfate
heparin binding protein
imb r1
phospholipase C gamma
protein p53
unclassified drug
antineoplastic agent
fibroblast growth factor 2
fibroblast growth factor receptor 1
heparin
messenger RNA
monoclonal antibody
antioxidant assay
apoptosis
Article
cancer survival
cell survival
controlled study
cross reaction
down regulation
drug protein binding
enzyme activation
enzyme linked immunosorbent assay
human
human cell
immunohistochemistry
methodology
proof of concept study
protein domain
protein targeting
quantitative analysis
real time polymerase chain reaction
sequence homology
signal transduction
Student t test
upregulation
Western blotting
antagonists and inhibitors
biopsy
cell proliferation
chemistry
drug effects
gene expression regulation
genetics
metabolism
molecularly targeted therapy
Neoplasms
pathology
protein domain
Antibodies, Monoclonal
Antineoplastic Agents
Apoptosis
Biopsy
Cell Proliferation
Fibroblast Growth Factor 2
Gene Expression Regulation, Neoplastic
Heparin
Humans
Molecular Targeted Therapy
Neoplasms
Protein Interaction Domains and Motifs
Receptor, Fibroblast Growth Factor, Type 1
RNA, Messenger
Signal Transduction
Ling L.
Tan S.K.
Goh T.H.
Cheung E.
VICTOR NURCOMBE
van Wijnen A.J.
Cool S.M.
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
description 10.1186/s12943-015-0391-4
author2 BIOCHEMISTRY
author_facet BIOCHEMISTRY
Ling L.
Tan S.K.
Goh T.H.
Cheung E.
VICTOR NURCOMBE
van Wijnen A.J.
Cool S.M.
format Article
author Ling L.
Tan S.K.
Goh T.H.
Cheung E.
VICTOR NURCOMBE
van Wijnen A.J.
Cool S.M.
author_sort Ling L.
title Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
title_short Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
title_full Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
title_fullStr Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
title_full_unstemmed Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
title_sort targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
publisher BioMed Central Ltd.
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/174283
_version_ 1800914226839027712