Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
10.1186/s12943-015-0391-4
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2020
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sg-nus-scholar.10635-1742832024-04-18T07:32:45Z Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy Ling L. Tan S.K. Goh T.H. Cheung E. VICTOR NURCOMBE van Wijnen A.J. Cool S.M. BIOCHEMISTRY ORTHOPAEDIC SURGERY 1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea 3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid antibodies,antisera and immunoglobulins antineoplastic agent fibroblast growth factor receptor 1 heparan sulfate heparin binding protein imb r1 phospholipase C gamma protein p53 unclassified drug antineoplastic agent fibroblast growth factor 2 fibroblast growth factor receptor 1 heparin messenger RNA monoclonal antibody antioxidant assay apoptosis Article cancer survival cell survival controlled study cross reaction down regulation drug protein binding enzyme activation enzyme linked immunosorbent assay human human cell immunohistochemistry methodology proof of concept study protein domain protein targeting quantitative analysis real time polymerase chain reaction sequence homology signal transduction Student t test upregulation Western blotting antagonists and inhibitors biopsy cell proliferation chemistry drug effects gene expression regulation genetics metabolism molecularly targeted therapy Neoplasms pathology protein domain Antibodies, Monoclonal Antineoplastic Agents Apoptosis Biopsy Cell Proliferation Fibroblast Growth Factor 2 Gene Expression Regulation, Neoplastic Heparin Humans Molecular Targeted Therapy Neoplasms Protein Interaction Domains and Motifs Receptor, Fibroblast Growth Factor, Type 1 RNA, Messenger Signal Transduction 10.1186/s12943-015-0391-4 Molecular Cancer 14 1 136 2020-09-04T02:09:47Z 2020-09-04T02:09:47Z 2015 Article Ling L., Tan S.K., Goh T.H., Cheung E., VICTOR NURCOMBE, van Wijnen A.J., Cool S.M. (2015). Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy. Molecular Cancer 14 (1) : 136. ScholarBank@NUS Repository. https://doi.org/10.1186/s12943-015-0391-4 14764598 https://scholarbank.nus.edu.sg/handle/10635/174283 BioMed Central Ltd. Unpaywall 20200831 |
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1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea 3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid antibodies,antisera and immunoglobulins antineoplastic agent fibroblast growth factor receptor 1 heparan sulfate heparin binding protein imb r1 phospholipase C gamma protein p53 unclassified drug antineoplastic agent fibroblast growth factor 2 fibroblast growth factor receptor 1 heparin messenger RNA monoclonal antibody antioxidant assay apoptosis Article cancer survival cell survival controlled study cross reaction down regulation drug protein binding enzyme activation enzyme linked immunosorbent assay human human cell immunohistochemistry methodology proof of concept study protein domain protein targeting quantitative analysis real time polymerase chain reaction sequence homology signal transduction Student t test upregulation Western blotting antagonists and inhibitors biopsy cell proliferation chemistry drug effects gene expression regulation genetics metabolism molecularly targeted therapy Neoplasms pathology protein domain Antibodies, Monoclonal Antineoplastic Agents Apoptosis Biopsy Cell Proliferation Fibroblast Growth Factor 2 Gene Expression Regulation, Neoplastic Heparin Humans Molecular Targeted Therapy Neoplasms Protein Interaction Domains and Motifs Receptor, Fibroblast Growth Factor, Type 1 RNA, Messenger Signal Transduction |
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1 tert butyl 3 [6 (3,5 dimethoxyphenyl) 2 (4 diethylaminobutylamino)pyrido[2,3 d]pyrimidin 7 yl]urea 3 [4 methyl 2 (2 oxo 3 indolinylmethylidenyl) 3 pyrrolyl]propionic acid antibodies,antisera and immunoglobulins antineoplastic agent fibroblast growth factor receptor 1 heparan sulfate heparin binding protein imb r1 phospholipase C gamma protein p53 unclassified drug antineoplastic agent fibroblast growth factor 2 fibroblast growth factor receptor 1 heparin messenger RNA monoclonal antibody antioxidant assay apoptosis Article cancer survival cell survival controlled study cross reaction down regulation drug protein binding enzyme activation enzyme linked immunosorbent assay human human cell immunohistochemistry methodology proof of concept study protein domain protein targeting quantitative analysis real time polymerase chain reaction sequence homology signal transduction Student t test upregulation Western blotting antagonists and inhibitors biopsy cell proliferation chemistry drug effects gene expression regulation genetics metabolism molecularly targeted therapy Neoplasms pathology protein domain Antibodies, Monoclonal Antineoplastic Agents Apoptosis Biopsy Cell Proliferation Fibroblast Growth Factor 2 Gene Expression Regulation, Neoplastic Heparin Humans Molecular Targeted Therapy Neoplasms Protein Interaction Domains and Motifs Receptor, Fibroblast Growth Factor, Type 1 RNA, Messenger Signal Transduction Ling L. Tan S.K. Goh T.H. Cheung E. VICTOR NURCOMBE van Wijnen A.J. Cool S.M. Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
description |
10.1186/s12943-015-0391-4 |
author2 |
BIOCHEMISTRY |
author_facet |
BIOCHEMISTRY Ling L. Tan S.K. Goh T.H. Cheung E. VICTOR NURCOMBE van Wijnen A.J. Cool S.M. |
format |
Article |
author |
Ling L. Tan S.K. Goh T.H. Cheung E. VICTOR NURCOMBE van Wijnen A.J. Cool S.M. |
author_sort |
Ling L. |
title |
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
title_short |
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
title_full |
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
title_fullStr |
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
title_full_unstemmed |
Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
title_sort |
targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy |
publisher |
BioMed Central Ltd. |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/174283 |
_version_ |
1800914226839027712 |