Novel SNP improves differential survivability and mortality in non-small cell lung cancer patients

• Main Authors: Mah, T.L, Yap, X.N.A, Limviphuvadh, V, Li, N, Sridharan, S, Kuralmani, V, Feng, M, Liem, N, Adhikari, S, Yong, W.P, Soo, R.A, Maurer-Stroh, S, Eisenhaber, F, Tong, J.C
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: BioMed Central Ltd. 2020
• Subjects: DNA directed DNA polymerase alpha; gemcitabine; deoxycytidine; DNA directed DNA polymerase beta; tumor marker; adult; aged; Article; cancer mortality; cancer survival; carcinogenesis; cellular distribution; clinical article; confocal laser microscopy; controlled study; DNA replication; female; genetic association; genetic variability; human; human cell; male; non small cell lung cancer; oncogene; outcome assessment; overall survival; POLA2 gene; protein analysis; protein localization; single nucleotide polymorphism; survival time; active transport; analogs and derivatives; biology; Carcinoma, Non-Small-Cell Lung; cell nucleus; chemical structure; chemistry; genetics; genotype; Lung Neoplasms; metabolism; middle aged; mortality; mutation; prognosis; protein conformation; survival; Active Transport, Cell Nucleus; Adult; Aged; Biomarkers, Tumor; Cell Nucleus; Computational Biology; Deoxycytidine; DNA Polymerase I; Female; Genotype; Humans; Male; Middle Aged; Models, Molecular; Mutation; Polymorphism, Single Nucleotide; Prognosis; Protein Conformation; Survival Analysis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174295
• Institution: National University of Singapore

10.1186/1471-2164-15-S9-S20