Orally disintegrating tablets containing melt extruded amorphous solid dispersion of tacrolimus for dissolution enhancement

• Main Authors: Ponnammal, P, Kanaujia, P, Yani, Y, Ng, W.K, Tan, R.B.H
• Other Authors: PHARMACY
• Format: Article
• Published: MDPI AG 2020
• Subjects: hydroxypropylcellulose; polyvinylpyrrolidone vinyl acetate; povidone derivative; tacrolimus; unclassified drug; amorphous solid dispersion; Article; controlled study; differential scanning calorimetry; dispersion; drug delivery system; drug formulation; drug solubility; drug stability; high performance liquid chromatography; hydrogen bond; infrared spectroscopy; molecular dynamics; molecular model; powder X ray diffraction; slow drug release; tablet disintegration time; thermogravimetry; X ray diffraction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174360
• Institution: National University of Singapore

10.3390/pharmaceutics10010035