Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment

• Main Authors: Moraes L.A., Kar S., Foo S.L., Gu T., Toh Y.Q., Ampomah P.B., Sachaphibulkij K., Yap G., Zharkova O., Lukman H.M., Fairhurst A.-M., Kumar A.P., Lim L.H.K.
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: annexin A1, mouse; formyl peptide receptor 2, mouse; formylpeptide receptor; immunoglobulin enhancer binding protein; lipocortin 1; mitogen activated protein kinase; animal; cell motion; cell proliferation; experimental mammary neoplasm; female; genetics; immunology; macrophage; metabolism; mouse; pathology; signal transduction; tumor cell culture; tumor microenvironment; Animals; Annexin A1; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Macrophages; Mammary Neoplasms, Animal; Mice; NF-kappa B; Receptors, Formyl Peptide; Signal Transduction; Tumor Cells, Cultured; Tumor Microenvironment
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174373
• Institution: National University of Singapore

10.1038/s41598-017-17622-5