Protective smell of hydrogen sulfide and polysulfide in cisplatin-induced nephrotoxicity

• Main Authors: Cao X., Zhang W., Moore P.K., Bian J.
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Review
• Published: 2020
• Subjects: 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene; 2 (2 amino 3 methoxyphenyl)chromone; acetylcysteine; carrier proteins and binding proteins; cisplatin; copper transporter; cystathionine gamma lyase; cysteine; cytochrome P450; cytochrome P450 2E1; cytokine; homocysteine; hydrogen polysulfide; hydrogen sulfide; interleukin 10; interleukin 18; interleukin 1beta; interleukin 2; messenger RNA; mitogen activated protein kinase; mitogen activated protein kinase kinase 1; monocyte chemotactic protein 1; organic cation transporter 2; reactive oxygen metabolite; reduced nicotinamide adenine dinucleotide phosphate oxidase; stress activated protein kinase; sulfide; synaptophysin; tumor necrosis factor; unclassified drug; GYY 4137; morpholine derivative; phosphorothioic acid derivative; antiapoptotic activity; antineoplastic activity; antioxidant activity; biosynthesis; cell death; clinical trial (topic); dimerization; down regulation; drug accumulation; enzyme activity; enzyme inhibition; human; hydrogen sulfide biosynthesis; inflammation; kidney microsome; MAPK signaling; molecular mechanics; nephrotoxicity; nonhuman; oxidative stress; pathophysiology; protein expression; renal protection; Review; risk factor; signal transduction; therapy effect; chemically induced; complication; drug effect; gene expression regulation; genetics; kidney; kidney disease; metabolism; neoplasm; odor; oxidation reduction reaction; pathology; Cisplatin; Cystathionine gamma-Lyase; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Sulfide; Kidney; Kidney Diseases; Morpholines; Neoplasms; Organothiophosphorus Compounds; Oxidation-Reduction; Reactive Oxygen Species; Smell
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174660
• Institution: National University of Singapore

10.3390/ijms20020313