Normalizing' the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrin

• Main Authors: Abu-Tayeh, H, Weidenfeld, K, Zhilin-Roth, A, Schif-Zuck, S, Thaler, S, Cotarelo, C, Tan, T.Z, Thiery, J.P, Green, J.E, Klorin, G, Sabo, E, Sleeman, J.P, Tzukerman, M, Barkan, D
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: alpha6 integrin; CD24 antigen; cyclin dependent kinase inhibitor 1A; epithelial cell adhesion molecule; Notch4 receptor; vitronectin receptor; Notch receptor; NOTCH4 protein, human; oncoprotein; animal experiment; animal model; apoptosis; Article; basement membrane; breast cancer cell line; breast carcinoma; breast epithelium; breast hyperplasia; cancer growth; cancer staging; cell differentiation; cell proliferation; controlled study; cytoplasm; down regulation; human; human tissue; intraductal carcinoma; luminal A breast cancer; mouse; nonhuman; nuclear size; phenotype; priority journal; protein expression; protein localization; three dimensional imaging; tumor differentiation; tumor microenvironment; acinar cell; breast tumor; cancer stem cell; embryonic stem cell; female; gene silencing; hyperplasia; MCF-7 cell line; metabolism; multicellular spheroid; pathology; signal transduction; teratoma; tumor cell line; Acinar Cells; Basement Membrane; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Embryonic Stem Cells; Female; Gene Knockdown Techniques; Humans; Hyperplasia; Integrin alphaVbeta3; MCF-7 Cells; Neoplastic Stem Cells; Organoids; Phenotype; Proto-Oncogene Proteins; Receptors, Notch; Signal Transduction; Spheroids, Cellular; Teratoma
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174910
• Institution: National University of Singapore

10.1038/cddis.2016.387