Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors

• Main Authors: Cheng, H, Ang, H.Y.-K, El Farran, C.A, Li, P, Fang, H.T, Liu, T.M, Kong, S.L, Chin, M.L, Ling, W.Y, Lim, E.K.H, Li, H, Huber, T, Loh, K.M, Loh, Y.-H, Lim, B
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: BMI1 protein; transcription factor; transcription factor lmo2; transcription factor RUNX1; transcription factor TAL1; unclassified drug; acetylcholinesterase; bone morphogenetic protein; mitogen activated protein kinase; mitogen activated protein kinase kinase; blood; cells and cell components; embryonic development; enzyme; enzyme activity; gene expression; protein; rodent; animal cell; animal experiment; Article; bone marrow cell; controlled study; fibroblast; hematopoiesis; in vitro study; in vivo study; lymphoid cell; lymphoid progenitor cell; megakaryocyte; myeloerythroid progenitor cell; nonhuman; nuclear reprogramming; nucleotide sequence; stem cell; upregulation; animal; cell differentiation; gene expression regulation; genetics; genomics; hematopoietic stem cell; human; metabolism; mouse; phagocyte; physiology; protein microarray; Mus; Acetylcholinesterase; Animals; Bone Morphogenetic Proteins; Cell Differentiation; Cellular Reprogramming; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Genomics; Hematopoietic Stem Cells; Humans; Megakaryocytes; Mice; Mitogen-Activated Protein Kinase Kinases; Myeloid Cells; Phagocytes; Protein Array Analysis; Transcription Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174915
• Institution: National University of Singapore

10.1038/ncomms13396