Development of background-free tame fluorescent probes for intracellular live cell imaging

• Main Authors: Alamudi, S.H, Satapathy, R, Kim, J, Su, D, Ren, H, Das, R, Hu, L, Alvarado-Martínez, E, Lee, J.Y, Hoppmann, C, Penã-Cabrera, E, Ha, H.-H, Park, H.-S, Wang, L, Chang, Y.-T
• Other Authors: DEPT OF CHEMISTRY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: alpha tubulin; fluorescent dye; 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; azide; boron derivative; cyclooctane derivative; recombinant protein; cell organelle; cells and cell components; cellular automaton; fluorescence; permeability; protein; solubility; animal cell; Article; cell function; cell membrane; cell membrane permeability; cell proliferation; controlled study; genetic transfection; high throughput screening; imaging; in vitro study; lipophilicity; live cell imaging; nonhuman; quantitative structure activity relation; reliability; surface area; Western blotting; animal; chemistry; CHO cell line; Cricetulus; drug design; gene expression; genetics; Golgi complex; human; lysosome; metabolism; mitochondrion; molecular imaging; nucleolus; osteoblast; procedures; signal noise ratio; staining; synthesis; tumor cell line; ultrastructure; Animals; Azides; Boron Compounds; Cell Line, Tumor; Cell Nucleolus; CHO Cells; Cyclooctanes; Drug Design; Fluorescent Dyes; Gene Expression; Golgi Apparatus; High-Throughput Screening Assays; Humans; Lysosomes; Mitochondria; Molecular Imaging; Osteoblasts; Recombinant Proteins; Signal-To-Noise Ratio; Staining and Labeling
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174954
• Institution: National University of Singapore

10.1038/ncomms11964