Acetylation of C/EBP? inhibits its granulopoietic function

• Main Authors: Bararia, D, Kwok, H.S, Welner, R.S, Numata, A, Sárosi, M.B, Yang, H, Wee, S, Tschuri, S, Ray, D, Weigert, O, Levantini, E, Ebralidze, A.K, Gunaratne, J, Tenen, D.G
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: CCAAT enhancer binding protein alpha; granulocyte colony stimulating factor; histone acetyltransferase GCN5; lysine; histone acetyltransferase PCAF; p300-CBP-associated factor; acetylation; acute myeloblastic leukemia; Article; bone marrow cell; cell differentiation; controlled study; DNA binding; down regulation; granulopoiesis; human; human cell; leukemia cell; myeloid leukemia; myeloid leukemia cell line; acute myeloid leukemia; cytology; gel mobility shift assay; gene expression regulation; genetics; granulocyte; HEK293 cell line; immunoblotting; immunoprecipitation; liquid chromatography; mass spectrometry; metabolism; myelopoiesis; tumor cell line; Acetylation; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line, Tumor; Chromatography, Liquid; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocytes; HEK293 Cells; Humans; Immunoblotting; Immunoprecipitation; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mass Spectrometry; Myelopoiesis; p300-CBP Transcription Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174982
• Institution: National University of Singapore

10.1038/ncomms10968