Bidirectional modulation of hippocampal synaptic plasticity by Dopaminergic D4-receptors in the CA1 area of hippocampus

• Main Authors: Navakkode S., Chew K.C.M., Tay S.J.N., Lin Q., Behnisch T., Soong T.W.
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: benzamide derivative; calcium calmodulin dependent protein kinase II; dopamine 4 receptor; Grin3a protein, rat; membrane protein; N-((4-(2-cyanophenyl)-1-piperazinyl)methyl)-3-methylbenzamide; piperazine derivative; animal; antagonists and inhibitors; dopaminergic nerve cell; drug effect; gene expression regulation; genetics; hippocampal CA1 region; hippocampus; human; long term depression; long term potentiation; nerve cell network; nerve cell plasticity; pathophysiology; physiology; protein synthesis; rat; synapse; synaptic transmission; Animals; Benzamides; CA1 Region, Hippocampal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dopaminergic Neurons; Gene Expression Regulation; Hippocampus; Humans; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Glycoproteins; Nerve Net; Neuronal Plasticity; Piperazines; Protein Biosynthesis; Rats; Receptors, Dopamine D4; Synapses; Synaptic Transmission
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175093
• Institution: National University of Singapore

10.1038/s41598-017-15917-1