Expression of DHA-Metabolizing Enzyme Alox15 is Regulated by Selective Histone Acetylation in Neuroblastoma Cells

• Main Authors: Ho, C.F.-Y, Bon, C.P.-E, Ng, Y.-K, Herr, D.R, Wu, J.-S, Lin, T.-N, Ong, W.-Y
• Other Authors: ANATOMY
• Format: Article
• Published: Springer New York LLC 2020
• Subjects: butyric acid; depsipeptide; docosahexaenoic acid; entinostat; enzyme; histone acetyltransferase; histone deacetylase inhibitor; messenger RNA; protein Alox15; retinoic acid; trichostatin A; unclassified drug; ALOX15 protein, human; Alox15 protein, mouse; arachidonate 12 lipoxygenase; arachidonate 15 lipoxygenase; histone; animal cell; Article; brain cell; brain development; controlled study; enzyme inhibition; epigenetics; gene expression; histone acetylation; histone modification; human; human cell; in vitro study; mouse; nerve cell differentiation; neurite outgrowth; neuroblastoma cell; nonhuman; priority journal; protein expression; regulatory mechanism; SH-SY5Y cell line; upregulation; acetylation; animal; cell differentiation; cell proliferation; drug effect; genetic epigenesis; metabolism; nerve cell; neural stem cell; neuroblastoma; Acetylation; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Cell Differentiation; Cell Proliferation; Docosahexaenoic Acids; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Mice; Neural Stem Cells; Neuroblastoma; Neurons
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175124
• Institution: National University of Singapore

10.1007/s11064-017-2448-9