Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex

• Main Authors: Kristal Kaan, H.Y, Chan, S.W, Tan, S.K.J, Guo, F, Lim, C.J, Hong, W, Song, H
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: DNA binding protein; fusion protein; muscle protein; phosphoprotein; protein binding; signal transducing adaptor protein; Taz protein, mouse; Tead4 protein, mouse; transcription factor; Yap protein, mouse; animal; binding site; chemistry; metabolism; molecular model; mouse; protein conformation; protein domain; protein multimerization; structure activity relation; Adaptor Proteins, Signal Transducing; Animals; Binding Sites; DNA-Binding Proteins; Mice; Models, Molecular; Muscle Proteins; Phosphoproteins; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Fusion Proteins; Structure-Activity Relationship; Transcription Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175186
• Institution: National University of Singapore

10.1038/s41598-017-02219-9