TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis

• Main Authors: Rossetti, M, Spreafico, R, Consolaro, A, Leong, J.Y, Chua, C, Massa, M, Saidin, S, Magni-Manzoni, S, Arkachaisri, T, Wallace, C.A, Gattorno, M, Martini, A, Lovell, D.J, Albani, S
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: BMJ Publishing Group 2020
• Subjects: T lymphocyte receptor beta chain; transcription factor FOXP3; lymphocyte antigen receptor; adolescent; adult; adult disease; adult rheumatoid arthritis; amino acid sequence; Article; blood; clinical article; cohort analysis; controlled study; demethylation; DNA methylation; female; flow cytometry; human; human cell; juvenile rheumatoid arthritis; lymphocyte recirculation; male; molecular cloning; pathogenesis; prospective study; protein stability; regulatory T lymphocyte; rheumatoid arthritis; synovial fluid; T lymphocyte subpopulation; child; cytology; genetics; immunology; preschool child; synovium; T lymphocyte receptor gene; young adult; Adolescent; Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; DNA Methylation; Female; Flow Cytometry; Genes, T-Cell Receptor beta; Humans; Male; Receptors, Antigen, T-Cell; Synovial Fluid; Synovial Membrane; T-Lymphocytes, Regulatory; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175237
• Institution: National University of Singapore

10.1136/annrheumdis-2015-208992