Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA

• Main Authors: Tegtmeyer, N, Moodley, Y, Yamaoka, Y, Pernitzsch, S.R, Schmidt, V, Traverso, F.R, Schmidt, T.P, Rad, R, Yeoh, K.G, Bow, H, Torres, J, Gerhard, M, Schneider, G, Wessler, S, Backert, S
• Other Authors: DEPT OF MEDICINE
• Published: Blackwell Publishing Ltd 2020
• Subjects: HtrA protein; oligomer; serine proteinase; unclassified drug; uvomorulin; bacterial protein; cadherin; Article; bacterium isolate; cell function; controlled study; DNA flanking region; extracellular space; gene expression regulation; gene inactivation; gene repression; gene structure; genetic conservation; genetic screening; genetic variability; Helicobacter infection; Helicobacter pylori; htrA gene; human; human tissue; intracellular space; major clinical study; mutagenesis; nonhuman; operon; priority journal; protein cleavage; protein degradation; RNA sequence; sequence analysis; stomach biopsy; transcription regulation; bacterial gene; enzymology; essential gene; genetic variation; genetics; metabolism; molecular evolution; molecular genetics; nucleotide sequence; periplasm; Bacterial Proteins; Base Sequence; Cadherins; Evolution, Molecular; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Genes, Bacterial; Genes, Essential; Genetic Variation; Humans; Molecular Sequence Data; Operon; Periplasm; Sequence Analysis, RNA; Serine Endopeptidases
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175262
• Institution: National University of Singapore

10.1111/mmi.13276