Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

• Main Authors: Li Q., Wojciechowski R., Simpson C.L., Hysi P.G., Verhoeven V.J.M., Ikram M.K., Höhn R., Vitart V., Hewitt A.W., Oexle K., Mäkelä K.-M., Ho D.W.H., Chew E., Mihailov E., Smith G.D., Biino G., Rudan I., Seppala I., Kaprio J., Craig J.E., Polling J.R., MacGregor S., Tideman J.-W., Fondran J.R., Wang J.J., Liao J., Zhao J.H., Xie J., Bailey Wilson J.E., Burdon K.P., Khaw K.-T., Yamashiro K., Pirastu M., Portas L., Farrer L., Raffel L.J., Chen L.J., Xu L., Deangelis M.M., Morrison M., Schache M., Cotch M.-F., Miyake M., Fan Q., Fossarello M., He M., Yoshimura N., Wareham N.J., Mizuki N., Pfeiffer N., Polasek O., Tam P.O., Foster P.J., Chen P., Cheng C.-Y., Gharahkhani P., Fogarty R.D., Luben R.N., Igo R.P., Jr., Klein R., Mohsen Hosseini S., Janmahasatian S., Feng S., Panda-Jonas S., St Pourcain B., Iyengar S.K., Lass J.H., Rantanen T., Haller T., Nangia V., Jhanji V., Chen W., Zhou X., Guo X., Li X., McMahon G., Vatavuk Z., The CREAM consortium, Kemp J.P., Northstone K., Rahi J.S., Cumberland P.M., Martin N.G., Sanfilippo P.G., Lu Y., Wang Y.X., Hayward C., Polašek O., Campbell H., Bencic G., Wright A.F., Wedenoja J., Zeller T., Schillert A., Mirshahi A., Lackner K., Yip S.P., Yap M.K.H., Ried J.S., Gieger C., Murgia F., Wilson J.F., Fleck B., Yazar S., Vingerling J.R., Hofman A., Uitterlinden A., Rivadeneira F., Amin N., Karssen L., Oostra B.A., Teo Y.-Y., Tai E.S., Vithana E., Barathi V., Zheng Y., Siantar R.G., Neelam K., Shin Y., Lam J., Yonova-Doing E., Venturini C., Hosseini S.M., Wong H.-S., Lehtimäki T., Kähönen M., Raitakari O., Timpson N.J., Evans D.M., Khor C.-C., Aung T., Young T.L., Mitchell P., Klein B., van Duijn C.M., Meitinger T., Jonas J.B., Baird P.N., Mackey D.A., Wong T.Y., Saw S.-M., Pärssinen O., Stambolian D., Hammond C.J., Klaver C.C.W., Williams C., Paterson A.D., Bailey-Wilson J.E., Guggenheim J.A., Meguro A., Young A.L., Veluchamy A.B., Metspalu A., Döring A., Khawaja A.P., Klein B.E., Pourcain B.S., Delcourt C., Maubaret C., Pang C.P.
• Other Authors: OPHTHALMOLOGY
• Format: Article
• Published: Springer 2020
• Subjects: neurexin; neurexin 1; unclassified drug; genetic marker; high mobility group protein; nerve cell adhesion molecule; nerve protein; NRXN1 protein, human; TOX protein, human; adult; Article; Asian; astigmatism; Chinese; controlled study; European; female; gene frequency; gene locus; genetic association; genetic risk; genetic variability; genotype; human; logistic regression analysis; major clinical study; male; meta analysis (topic); priority journal; refractive astigmatism; single nucleotide polymorphism; age; Asian continental ancestry group; Caucasian; cohort analysis; genetics; genome-wide association study; meta analysis; middle aged; pathology; Adult; Age Factors; Asian Continental Ancestry Group; Astigmatism; Cell Adhesion Molecules, Neuronal; Cohort Studies; European Continental Ancestry Group; Female; Genetic Markers; Genome-Wide Association Study; High Mobility Group Proteins; Humans; Male; Middle Aged; Nerve Tissue Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175292
• Institution: National University of Singapore

10.1007/s00439-014-1500-y