CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer

• Main Authors: Roy R.K., Hoppe M.M., Srivastava S., Samanta A., Sharma N., Tan K.T., Yang H., Voon D.C., Pang B., Teh M., Murata-Kamiya N., Hatakeyama M., Chang Y.-T., Yong W.P., Ito Y., Ho K.Y., Tan P., Soong R., Koeffler P.H., Yeoh K.G., Jeyasekharan A.D.
• Other Authors: BIOMEDICAL ENGINEERING
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: biological marker; CagA protein; cancer antibody; carcinoembryonic antigen related cell adhesion molecule 6; transcriptome; bacterial antigen; bacterial protein; cagA protein, Helicobacter pylori; CEACAM6 protein, human; cell adhesion molecule; glycosylphosphatidylinositol anchored protein; leukocyte antigen; tumor marker; Article; bacterium identification; binding affinity; binding site; cancer diagnosis; controlled study; disease activity; gene expression; Helicobacter pylori; human; human cell; immunohistochemistry; in vitro study; molecular dynamics; molecular pathology; nonhuman; protein binding; protein determination; protein expression; protein function; quantitative analysis; stomach cancer; stomach carcinogenesis; tissue level; tissue microarray; upregulation; animal; fluorescent antibody technique; Helicobacter infection; metabolism; mouse; physiology; stomach tumor; Animals; Antigens, Bacterial; Antigens, CD; Bacterial Proteins; Biomarkers, Tumor; Cell Adhesion Molecules; Fluorescent Antibody Technique; GPI-Linked Proteins; Helicobacter Infections; Humans; Mice; Stomach Neoplasms; Up-Regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175455
• Institution: National University of Singapore

10.18632/oncotarget.10528