PRL-3 activates mTORC1 in Cancer Progression

• Main Authors: Ye, Z, Al-Aidaroos, A.Q.O, Park, J.E, Yuen, H.F, Zhang, S.D, Gupta, A, Lin, Y, Shen, H.-M, Zeng, Q
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: gelatinase A; mechanistic target of rapamycin complex 1; MMP2 protein, human; monomeric guanine nucleotide binding protein; multiprotein complex; neuropeptide; protein binding; protein kinase B; protein tyrosine phosphatase; PTP4A3 protein, human; RHEB protein, human; target of rapamycin kinase; tuberin; tumor protein; tumor suppressor protein; cell motion; disease course; enzyme activation; enzymology; human; lysosome; metabolism; pathology; physiology; protein transport; secretion (process); signal transduction; stomach tumor; tumor cell line; Cell Line, Tumor; Cell Movement; Disease Progression; Enzyme Activation; Humans; Lysosomes; Matrix Metalloproteinase 2; Monomeric GTP-Binding Proteins; Multiprotein Complexes; Neoplasm Proteins; Neuropeptides; Protein Binding; Protein Transport; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175464
• Institution: National University of Singapore

10.1038/srep17046