New loci and coding variants confer risk for age-related macular degeneration in East Asians

• Main Authors: Cheng C.-Y., Yamashiro K., Jia Chen L.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: cholesterol ester transfer protein; high density lipoprotein cholesterol; CETP protein, human; age structure; blindness; cardiovascular disease; genetics; genome; health risk; mutation; age related macular degeneration; allele; Article; cholesterol blood level; controlled study; disease predisposition; East Asian; gene locus; gene mutation; gene replication; genetic association; genetic identification; genetic risk; genetic variability; genotype; human; ischemic heart disease; major clinical study; mutational load; phenotype; Asian continental ancestry group; blood; case control study; cohort analysis; coronary artery disease; exome; genetic predisposition; genome-wide association study; macular degeneration; reproducibility; risk factor; single nucleotide polymorphism; Europe; Far East; Asian Continental Ancestry Group; Case-Control Studies; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cohort Studies; Coronary Disease; Exome; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Macular Degeneration; Mutation; Polymorphism, Single Nucleotide; Reproducibility of Results; Risk Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175516
• Institution: National University of Singapore

10.1038/ncomms7063