Diameter-dependent release of a cisplatin pro-drug from small and large functionalized carbon nanotubes

• Main Authors: Muzi L., Ménard-Moyon C., Russier J., Li J., Chin C.F., Ang W.H., Pastorin G., Risuleo G., Bianco A.
• Other Authors: DEPT OF CHEMISTRY
• Format: Article
• Published: Royal Society of Chemistry 2020
• Subjects: Biochemistry; Carbon; Carbon nanotubes; Cell death; Cytology; Diseases; Drug delivery; Macrophages; Mobile security; Multiwalled carbon nanotubes (MWCN); Pharmacokinetics; Platinum; Platinum compounds; Transmission electron microscopy; Tumors; Yarn; Cellular internalization; Chemotherapeutic drugs; Cytokine production; Flow cytometry analysis; Functionalized carbon nanotubes; Inflammatory response; Multidrug resistance; Transmission electron microscopy observation; Drug therapy; antineoplastic agent; carbon nanotube; cisplatin; delayed release formulation; nanocapsule; prodrug; absorption; administration and dosage; apoptosis; cell survival; chemistry; diffusion; drug effects; HeLa cell line; human; particle size; ultrastructure; Absorption, Physicochemical; Antineoplastic Agents; Apoptosis; Cell Survival; Cisplatin; Delayed-Action Preparations; Diffusion; HeLa Cells; Humans; Nanocapsules; Nanotubes, Carbon; Particle Size; Prodrugs
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175531
• Institution: National University of Singapore

10.1039/c5nr00220f