Ultrasmall glutathione-protected gold nanoclusters as next generation radiotherapy sensitizers with high tumor uptake and high renal clearance

• Main Authors: Zhang, X.-D, Luo, Z, Chen, J, Song, S, Yuan, X, Shen, X, Wang, H, Sun, Y, Gao, K, Zhang, L, Fan, S, Leong, D.T, Guo, M, Xie, J
• Other Authors: CHEMICAL & BIOMOLECULAR ENGINEERING
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: glutathione; gold; metal nanoparticle; radiosensitizing agent; animal; antibody specificity; Bagg albino mouse; blood; computer assisted tomography; drug effects; hydrodynamics; kidney; male; metabolism; neoplasm; pathology; radiography; scintiscanning; three dimensional imaging; time; tumor volume; ultrastructure; ultraviolet spectrophotometry; Animals; Glutathione; Gold; Hydrodynamics; Imaging, Three-Dimensional; Kidney; Male; Metal Nanoparticles; Mice, Inbred BALB C; Neoplasms; Organ Specificity; Radiation-Sensitizing Agents; Spectrophotometry, Ultraviolet; Time Factors; Tomography, X-Ray Computed; Tumor Burden
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175533
• Institution: National University of Singapore

10.1038/srep08669