Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

• Main Authors: Ng, M, Ndungo, E, Kaczmarek, M.E, Herbert, A.S, Binger, T, Kuehne, A.I, Jangra, R.K, Hawkins, J.A, Gifford, R.J, Biswas, R, Demogines, A, James, R.M, Yu, M, Brummelkamp, T.R, Drosten, C, Wang, L.-F, Kuhn, J.H, MЃller, M.A, Dye, J.M, Sawyer, S.L, Chandran, K
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: npc1 receptor; unclassified drug; virus receptor; membrane protein; animal cell; Article; bat; controlled study; CRISPR Cas system; Ebola hemorrhagic fever; Ebolavirus; epidemic; fluorescence microscopy; gene sequence; image analysis; nonhuman; polymerase chain reaction; reverse transcription polymerase chain reaction; Rousettus aegyptiacus; sequence analysis; virus transmission; animal; cell line; Filoviridae; host range; metabolism; physiology; virus attachment; Animals; Cell Line; Chiroptera; Host Specificity; Membrane Glycoproteins; Receptors, Virus; Virus Attachment
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175971
• Institution: National University of Singapore

10.7554/eLife.11785