Disease modeling using 3D organoids derived from human induced pluripotent stem cells

• Main Authors: Ho, B.X, Pek, N.M.Q, Soh, B.-S
• Other Authors: BIOLOGICAL SCIENCES
• Format: Review
• Published: 2020
• Subjects: biological marker; cystic fibrosis transmembrane conductance regulator; action potential; Alagille syndrome; autism; cell differentiation; colorectal cancer; communicable disease; CRISPR Cas system; cystic fibrosis; disease simulation; drug response; drug screening; extracellular matrix; fatty liver; gene editing; genetic disorder; human; induced pluripotent stem cell; inflammatory bowel disease; mesenchymal stem cell; microcephaly; microenvironment; necrotizing enterocolitis; nervous system malformation; neural stem cell; nonhuman; organoid; ovary cancer; prostate cancer; protein expression; regenerative medicine; Review; vascular smooth muscle cell; vascularization; Zika fever; antibody specificity; biological model; cytology; diseases; Disease; Humans; Induced Pluripotent Stem Cells; Models, Biological; Organ Specificity; Organoids
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176051
• Institution: National University of Singapore

10.3390/ijms19040936