Psychiatric polygenic risk associates with cortical morphology and functional organization in aging

• Main Authors: Lee, A, Shen, M, Qiu, A
• Other Authors: BIOMEDICAL ENGINEERING
• Format: Article
• Published: 2020
• Subjects: neurotrophin; somatomedin receptor; transcriptome; adult; aged; Article; brain region; cell aging; controlled study; echo planar imaging; female; frontal cortex; functional connectivity; functional magnetic resonance imaging; GABAergic transmission; gene interaction; genetic risk; genotype; human; image quality; major clinical study; male; mental disease; Mini Mental State Examination; nerve cell plasticity; nerve degeneration; neuroimaging; parietal lobe; signal transduction; superior temporal gyrus; synaptic transmission; synaptogenesis; aging; anatomy and histology; brain cortex; brain mapping; diagnostic imaging; genetic predisposition; genetics; middle aged; multifactorial inheritance; nerve tract; nuclear magnetic resonance imaging; physiology; risk factor; very elderly; young adult; Adult; Aged; Aged, 80 and over; Aging; Brain Mapping; Cerebral Cortex; Female; Genetic Predisposition to Disease; Humans; Magnetic Resonance Imaging; Male; Mental Disorders; Middle Aged; Multifactorial Inheritance; Neural Pathways; Risk Factors; Transcriptome; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176069
• Institution: National University of Singapore

10.1038/s41398-017-0036-z