Human stem cell-derived endothelial-hepatic platform for efficacy testing of vascular-protective metabolites from nutraceuticals

• Main Authors: Narmada, B.C, Goh, Y.T, Li, H, Sinha, S, Yu, H, Cheung, C
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: collagen type 1; endothelial nitric oxide synthase; fibroblast growth factor 2; genistein; immunoglobulin enhancer binding protein; interleukin 1beta; interleukin 8; low density lipoprotein; nutraceutical; quercetin; transforming growth factor beta; vasculotropin; protective agent; antiinflammatory activity; Article; controlled study; culture medium; drug metabolism; endothelium cell; enzyme linked immunosorbent assay; flow cytometry; fluorescence activated cell sorting; gene expression; HeLa cell line; human; human cell; human pluripotent stem cell derived endothelial cell; immunohistochemistry; liquid chromatography-mass spectrometry; liver cell carcinoma; liver protection; metabolite; pluripotent stem cell; protein transport; real time polymerase chain reaction; stem cell culture; uptake assay; vascularization; Western blotting; conditioned medium; cytology; dietary supplement; drug effect; endothelial progenitor cell; human embryonic stem cell; inflammation; liver; liver cell; metabolism; metabolome; pathology; pharmacology; Culture Media, Conditioned; Dietary Supplements; Endothelial Progenitor Cells; Genistein; Hepatocytes; Human Embryonic Stem Cells; Humans; Inflammation; Interleukin-1beta; Liver; Metabolome; Pluripotent Stem Cells; Protective Agents; Quercetin
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176099
• Institution: National University of Singapore

10.5966/sctm.2016-0129