A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions

• Main Authors: Tan, W.J, Cima, I, Choudhury, Y, Wei, X, Lim, J.C.T, Thike, A.A, Tan, M.-H, Tan, P.H
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: ABC transporter A8; apolipoprotein D; fibronectin; formaldehyde; macrophage inflammatory protein 3beta; paraffin; transcriptome; ABC transporter; ABCA8 protein, human; APOD protein, human; CCL19 protein, human; FN1 protein, human; PRAME protein, human; tumor antigen; ABCA8 gene; adolescent; adult; aged; APOD gene; area under the curve; Article; breast fibroepithelial lesion; breast tumor; CCL19 gene; clinical article; clinical feature; cohort analysis; controlled study; cystosarcoma phylloides; diagnostic accuracy; diagnostic test accuracy study; FN1 gene; gene; gene expression; gene expression profiling; genetic transcription; human; human tissue; machine learning; molecular diagnosis; multigene; polymerase chain reaction; PRAME gene; prediction; preoperative period; quantitative analysis; receiver operating characteristic; reverse transcription polymerase chain reaction; sensitivity and specificity; tumor classification; validation process; biopsy; biosynthesis; Breast Neoplasms; differential diagnosis; female; fibroadenoma; gene expression regulation; genetics; middle aged; pathology; phyllodes tumor; procedures; very elderly; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Apolipoproteins D; ATP-Binding Cassette Transporters; Biopsy; Chemokine CCL19; Diagnosis, Differential; Female; Fibroadenoma; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Phyllodes Tumor; Preoperative Period; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176133
• Institution: National University of Singapore

10.1186/s13058-016-0692-6