Induced pluripotency and gene editing in disease modelling: Perspectives and challenges

• Main Authors: Seah, Y.F.S, El Farran, C.A, Warrier, T, Xu, J, Loh, Y.-H
• Other Authors: BIOLOGY (NU)
• Format: Article
• Published: 2020
• Subjects: alkaline phosphatase; alpha 1 antitrypsin; caspase 9; leucine rich repeat kinase 2; microRNA; octamer transcription factor 4; stage specific embryo antigen 1; transcription activator like effector nuclease; transcription factor Sox2; transforming growth factor beta; zinc finger protein; adrenoleukodystrophy; Alzheimer disease; Article; clustered regularly interspaced short palindromic repeat; Crigler Najjar syndrome; DNA methylation; embryonic stem cell; fragile X syndrome; gene editing; gene targeting; glycogen storage disease type 1; herpes simplex; herpes zoster; human; nuclear reprogramming; pancreas adenocarcinoma; pluripotent stem cell; Prader Willi syndrome; progeria; telomere; transgene; Williams Beuren syndrome; animal; biological model; CRISPR Cas system; cytology; genetic engineering; induced pluripotent stem cell; metabolism; Animals; Cellular Reprogramming; CRISPR-Cas Systems; Gene Targeting; Genetic Engineering; Humans; Induced Pluripotent Stem Cells; Models, Biological; Transgenes
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/176139
• Institution: National University of Singapore

10.3390/ijms161226119