DJ-1 protects against cell death following acute cardiac ischemiareperfusion injury

• Main Authors: Dongworth, R.K, Mukherjee, U.A, Hall, A.R, Astin, R, Ong, S.-B, Yao, Z, Dyson, A, Szabadkai, G, Davidson, S.M, Yellon, D.M, Hausenloy, D.J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Published: 2020
• Subjects: 1,2,3,6 tetrahydro 1 methyl 4 phenylpyridine; adenosine triphosphate; calcium; DJ 1 protein; mitochondrial permeability transition pore; adult; animal experiment; animal model; animal tissue; article; cell death; cell protection; cell survival; controlled study; disease predisposition; echocardiography; electron microscopy; gene overexpression; heart infarction prevention; heart infarction size; heart mitochondrion; knockout gene; mitochondrial membrane potential; mitochondrial respiration; mitochondrion swelling; mouse; mutant; nonhuman; phenotype; priority journal; reperfusion injury; sarcomere length; wild type; Adenosine Triphosphate; Animals; Calcium; Cell Death; Cell Line; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oncogene Proteins; Transfection
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177770
• Institution: National University of Singapore

10.1038/cddis.2014.41