Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects

• Main Authors: Tilan, J.U, Lu, C, Galli, S, Izycka-Swieszewska, E, Earnest, J.P, Shabbir, A, Everhart, L.M, Wang, S, Martin, S, Horton, M, Mahajan, A, Christian, D, O'Neill, A, Wang, H, Zhuang, T, Czarnecka, M, Johnson, M.D, Toretsky, J.A, Kitlinska, J
• Other Authors: SURGERY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: aldehyde dehydrogenase; dipeptidyl peptidase IV; neuropeptide Y; neuropeptide Y [3-36]; neuropeptide Y1 receptor; neuropeptide Y2 receptor; neuropeptide Y5 receptor; unclassified drug; animal experiment; animal model; animal tissue; article; cancer growth; cancer inhibition; cancer stem cell; carcinogenesis; cell migration; cell proliferation; cell stimulation; clinical article; controlled study; enzyme activity; Ewing sarcoma; human; human cell; human tissue; hypoxia; mouse; nonhuman; protein analysis; protein expression; protein function; protein induction; protein secretion; receptor binding; sarcoma cell; tumor vascularization; Animals; Cell Growth Processes; Cell Hypoxia; Cell Line, Tumor; Dipeptidyl Peptidase 4; Heterografts; Humans; Mice; Mice, Nude; Mice, SCID; Neoplastic Stem Cells; Neovascularization, Pathologic; Neuropeptide Y; Receptors, Neuropeptide Y; Sarcoma, Ewing
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177782
• Institution: National University of Singapore

10.18632/oncotarget.1604