Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition

• Main Authors: Mohan, P, Castellsague, J, Jiang, J, Allen, K, Chen, H, Nemirovsky, O, Spyra, M, Hu, K, Kluwe, L, Pujana, M.A, Villanueva, A, Mautner, V.F, Keats, J.J, Dunn, S.E, Lazaro, C, Maxwell, C.A
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Published: Impact Journals LLC 2020
• Subjects: alisertib; aurora A kinase; hyaluronan mediated motility receptor protein; targeting protein for XKLP2; tumor protein; unclassified drug; animal cell; animal experiment; animal model; apoptosis; article; cancer cell culture; cancer inhibition; cancer stem cell; cell cycle regulation; cell differentiation; cell renewal; controlled study; drug sensitization; endoreduplication; enzyme activity; enzyme inhibition; gene; gene dosage; gene expression regulation; gene mutation; gene product; gene silencing; genetic disequilibrium; hyaluronan mediated motility receptor gene; in vivo study; male; malignant peripheral nerve sheath tumor; mouse; nonhuman
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177785
• Institution: National University of Singapore

10.18632/oncotarget.793