Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer

• Main Authors: Tan, H.L, Yong, C, Tan, B.Z, Fong, W.J, Padmanabhan, J, Chin, A, Ding, V, Lau, A, Zheng, L, Bi, X, Yang, Y, Choo, A
• Other Authors: BIOMEDICAL ENGINEERING
• Format: Article
• Published: 2020
• Subjects: immunological antineoplastic agent; monoclonal antibody; oncofetal antigens; tumor antigen; animal; Bagg albino mouse; drug screening; experimental neoplasm; female; human; human embryonic stem cell; immunology; nude mouse; pathology; tumor cell line; Animals; Antibodies, Monoclonal, Murine-Derived; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Cell Line, Tumor; Female; Human Embryonic Stem Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Xenograft Model Antitumor Assays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177811
• Institution: National University of Singapore

10.1038/s41598-018-30070-z