Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody

10.1038/s41598-018-26800-y

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Main Authors:	Wong, Y.H, Kumar, A, Liew, C.W, Tharakaraman, K, Srinivasaraghavan, K, Sasisekharan, R, Verma, C, Lescar, J
Other Authors:	BIOLOGY (NU)
Format:	Article
Published:	2020
Subjects:	epitope monoclonal antibody single chain fragment variable antibody virus envelope protein amino acid sequence animal antigen antibody complex binding site calorimetry chemistry classification cross reaction dengue Dengue virus genetics human immunology molecular dynamics mouse pathology protein tertiary structure sequence alignment serodiagnosis serotype virology Amino Acid Sequence Animals Antibodies, Monoclonal, Humanized Antigen-Antibody Complex Binding Sites Calorimetry Cross Reactions Dengue Dengue Virus Epitopes Humans Mice Molecular Dynamics Simulation Neutralization Tests Protein Structure, Tertiary Sequence Alignment Serogroup Single-Chain Antibodies Viral Envelope Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/177818
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1778182020-10-20T13:54:31Z Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody Wong, Y.H Kumar, A Liew, C.W Tharakaraman, K Srinivasaraghavan, K Sasisekharan, R Verma, C Lescar, J BIOLOGY (NU) DUKE-NUS MEDICAL SCHOOL epitope monoclonal antibody single chain fragment variable antibody virus envelope protein amino acid sequence animal antigen antibody complex binding site calorimetry chemistry classification cross reaction dengue Dengue virus genetics human immunology molecular dynamics mouse pathology protein tertiary structure sequence alignment serodiagnosis serotype virology Amino Acid Sequence Animals Antibodies, Monoclonal, Humanized Antigen-Antibody Complex Binding Sites Calorimetry Cross Reactions Dengue Dengue Virus Epitopes Humans Mice Molecular Dynamics Simulation Neutralization Tests Protein Structure, Tertiary Sequence Alignment Serogroup Single-Chain Antibodies Viral Envelope Proteins 10.1038/s41598-018-26800-y Scientific Reports 8 1 8449 2020-10-20T03:26:52Z 2020-10-20T03:26:52Z 2018 Article Wong, Y.H, Kumar, A, Liew, C.W, Tharakaraman, K, Srinivasaraghavan, K, Sasisekharan, R, Verma, C, Lescar, J (2018). Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody. Scientific Reports 8 (1) : 8449. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-018-26800-y 20452322 https://scholarbank.nus.edu.sg/handle/10635/177818 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	epitope monoclonal antibody single chain fragment variable antibody virus envelope protein amino acid sequence animal antigen antibody complex binding site calorimetry chemistry classification cross reaction dengue Dengue virus genetics human immunology molecular dynamics mouse pathology protein tertiary structure sequence alignment serodiagnosis serotype virology Amino Acid Sequence Animals Antibodies, Monoclonal, Humanized Antigen-Antibody Complex Binding Sites Calorimetry Cross Reactions Dengue Dengue Virus Epitopes Humans Mice Molecular Dynamics Simulation Neutralization Tests Protein Structure, Tertiary Sequence Alignment Serogroup Single-Chain Antibodies Viral Envelope Proteins
spellingShingle	epitope monoclonal antibody single chain fragment variable antibody virus envelope protein amino acid sequence animal antigen antibody complex binding site calorimetry chemistry classification cross reaction dengue Dengue virus genetics human immunology molecular dynamics mouse pathology protein tertiary structure sequence alignment serodiagnosis serotype virology Amino Acid Sequence Animals Antibodies, Monoclonal, Humanized Antigen-Antibody Complex Binding Sites Calorimetry Cross Reactions Dengue Dengue Virus Epitopes Humans Mice Molecular Dynamics Simulation Neutralization Tests Protein Structure, Tertiary Sequence Alignment Serogroup Single-Chain Antibodies Viral Envelope Proteins Wong, Y.H Kumar, A Liew, C.W Tharakaraman, K Srinivasaraghavan, K Sasisekharan, R Verma, C Lescar, J Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
description	10.1038/s41598-018-26800-y
author2	BIOLOGY (NU)
author_facet	BIOLOGY (NU) Wong, Y.H Kumar, A Liew, C.W Tharakaraman, K Srinivasaraghavan, K Sasisekharan, R Verma, C Lescar, J
format	Article
author	Wong, Y.H Kumar, A Liew, C.W Tharakaraman, K Srinivasaraghavan, K Sasisekharan, R Verma, C Lescar, J
author_sort	Wong, Y.H
title	Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
title_short	Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
title_full	Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
title_fullStr	Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
title_full_unstemmed	Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
title_sort	molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/177818
_version_	1681696269557301248

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody

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