Ophiopogonin D, a steroidal glycoside abrogates STAT3 signaling cascade and exhibits anti-cancer activity by causing GSH/GSSG imbalance in lung carcinoma

• Main Authors: Lee, J.H, Kim, C, Lee, S.-G, Sethi, G, Ahn, K.S
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: 2020
• Subjects: caspase; glutathione; glutathione disulfide; glycoside; ophiopogonin d; STAT3 protein; unclassified drug; animal experiment; animal model; animal tissue; antineoplastic activity; apoptosis; Article; cancer inhibition; controlled study; drug effect; drug inhibition; drug mechanism; enzyme activation; female; gene; gene expression; human; human cell; mouse; non small cell lung cancer; nonhuman; oxidative stress; signal transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177833
• Institution: National University of Singapore

10.3390/cancers10110427