Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis

• Main Authors: Uchii, M, Tamura, T, Suda, T, Kakuni, M, Tanaka, A, Miki, I
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: fibroblast growth factor 8; glycosaminoglycan polysulfate; interleukin 1alpha; iodoacetic acid; matrix metalloproteinase; monoclonal antibody; prostaglandin E2; proteinase; recombinant fibroblast growth factor; recombinant fibroblast growth factor 8; stromelysin; A73025; glycosaminoglycan; unclassified drug; animal cell; animal experiment; animal model; animal tissue; article; cartilage cell; cartilage degeneration; cell culture; cell hyperplasia; controlled study; disease exacerbation; enzyme release; enzyme synthesis; extracellular matrix; fibroblast; immunohistochemistry; knee osteoarthritis; male; meniscectomy; nonhuman; prostaglandin release; protein analysis; protein degradation; protein expression; protein function; protein secretion; rabbit; rat; synoviocyte; synovium; animal; articular cartilage; cell proliferation; chemically induced disorder; disease model; drug effect; intraarticular drug administration; metabolism; pathology; Sprague Dawley rat; Animals; Cartilage, Articular; Cell Proliferation; Cells, Cultured; Chondrocytes; Dinoprostone; Disease Models, Animal; Extracellular Matrix; Fibroblast Growth Factor 8; Glycosaminoglycans; Injections, Intra-Articular; Iodoacetic Acid; Male; Matrix Metalloproteinase 3; Osteoarthritis, Knee; Rabbits; Rats; Rats, Sprague-Dawley; Synovial Membrane
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177965
• Institution: National University of Singapore

10.1186/ar2474