Influenza vaccine-induced antibody responses are not impaired by frailty in the community-dwelling elderly with natural influenza exposure

• Main Authors: Narang, V, Lu, Y, Tan, C, Camous, X.F.N, Nyunt, S.Z, Carre, C, Mok, E.W.H, Wong, G, Maurer-Stroh, S, Abel, B, Burdin, N, Poidinger, M, Tambyah, P.A, Bosco, N, Visan, L, Ng, T.P, Larbi, A
• Other Authors: BIOLOGY
• Format: Article
• Published: 2020
• Subjects: cytokine; gamma interferon inducible protein 10; influenza vaccine; tumor necrosis factor; inactivated vaccine; neutralizing antibody; virus antibody; aged; antibody response; Article; cellular immunity; cognition; comparative study; depression; female; flow cytometry; frailty; gene expression; hemagglutination inhibition; human; humoral immunity; immune response; immunophenotyping; Influenza virus; innate immunity; major clinical study; male; microarray analysis; mortality; peripheral blood mononuclear cell; seasonal influenza; seroconversion; serodiagnosis; seroprevalence; virus load; virus neutralization; antibody production; blood; clinical trial; frail elderly; immunology; influenza; Influenza A virus (H1N1); Influenza A virus (H3N2); Influenza B virus; phase 4 clinical trial; Singapore; vaccination; virology; Aged; Antibodies, Neutralizing; Antibodies, Viral; Antibody Formation; Female; Frail Elderly; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza Vaccines; Influenza, Human; Male; Seroconversion; Vaccination; Vaccines, Inactivated
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178062
• Institution: National University of Singapore

10.3389/fimmu.2018.02465