Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by dimethyl fumarate

• Main Authors: Han, J, Ma, S, Gong, H, Liu, S, Lei, L, Hu, B, Xu, Y, Liu, H, Wu, D
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2020
• Subjects: antioxidant; fumaric acid dimethyl ester; glutathione transferase alpha; heme oxygenase 1; programmed death 1 receptor; acute graft versus host disease; animal cell; animal experiment; animal model; antioxidant activity; Article; bone marrow transplantation; CD25+ T lymphocyte; CD3+ T lymphocyte; CD4+ T lymphocyte; cell differentiation; cell proliferation; controlled study; cytotoxicity assay; enzyme linked immunosorbent assay; flow cytometry; gene expression; gene expression regulation; graft recipient; graft versus tumor effect; histopathology; immune response; immunofluorescence microscopy; immunofluorescence test; mixed lymphocyte reaction; mortality; mouse; nonhuman; real time polymerase chain reaction; regulatory T lymphocyte; T cell depletion; T lymphocyte; upregulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178133
• Institution: National University of Singapore

10.3389/fimmu.2017.01605