Ex-vivo expanded human NK cells express activating receptors that mediate cytotoxicity of allogeneic and autologous cancer cell lines by direct recognition and antibody directed cellular cytotoxicity

• Main Authors: Voskens, C.J, Watanabe, R, Rollins, S, Campana, D, Hasumi, K, Mann, D.L
• Other Authors: PAEDIATRICS
• Format: Article
• Published: BMC 2020
• Subjects: natural killer cell receptor; EGFR protein, human; epidermal growth factor receptor; immunoglobulin receptor; ligand; monoclonal antibody; allogeneic cancer cell; article; autologous cancer cell; cancer cell; cancer cell culture; cell expansion; cytotoxicity; ex vivo study; human; human cell; lymphocyte; natural killer cell; peripheral blood mononuclear cell; priority journal; protein expression; stomach cancer; antibody dependent cellular cytotoxicity; cell proliferation; cell separation; coculture; immunology; immunophenotyping; lymphocyte activation; phenotype; stomach tumor; time; tumor cell line; Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Cell Line, Tumor; Cell Proliferation; Cell Separation; Coculture Techniques; Humans; Immunophenotyping; Killer Cells, Natural; Ligands; Lymphocyte Activation; Phenotype; Receptor, Epidermal Growth Factor; Receptors, Immunologic; Stomach Neoplasms; Time Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178196
• Institution: National University of Singapore

10.1186/1756-9966-29-134