Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: Analysis of data from randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)

• Main Authors: Loong, S.L.E, Hwang, J.S.G, Li, H.H, Wee, J.T.S, Yap, S.P, Chua, M.L.K, Fong, K.W, Tan, T.W.K
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: BMC 2020
• Subjects: cisplatin; cyclooxygenase 2; fluorouracil; antineoplastic agent; PTGS2 protein, human; adjuvant therapy; adult; aged; article; cancer chemotherapy; cancer radiotherapy; cancer staging; cancer survival; cohort analysis; controlled study; female; human; human tissue; immunohistochemistry; major clinical study; male; multiple cycle treatment; nasopharynx carcinoma; overall survival; prognosis; protein expression; treatment response; adolescent; clinical trial; comparative study; enzymology; metabolism; middle aged; multimodality cancer therapy; nasopharynx tumor; phase 3 clinical trial; radiation dose; randomized controlled trial; survival rate; treatment outcome; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cyclooxygenase 2; Female; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178221
• Institution: National University of Singapore

10.1186/1748-717X-4-23