Motavizumab, a neutralizing anti-respiratory syncytial virus (Rsv) monoclonal antibody significantly modifies the local and systemic cytokine responses induced by Rsv in the mouse model

• Main Authors: Mejías, A, Chávez-Bueno, S, Raynor, M.B, Connolly, J, Kiener, P.A, Jafri, H.S, Ramilo, O
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: BMC 2020
• Subjects: chemokine; cytokine; gamma interferon; granulocyte macrophage colony stimulating factor; interleukin 10; interleukin 12p40; interleukin 12p70; interleukin 13; interleukin 17; interleukin 1alpha; interleukin 1beta; interleukin 2; interleukin 3; interleukin 4; interleukin 5; interleukin 6; interleukin 8; monoclonal antibody; monocyte chemotactic protein 1; motavizumab; neutralizing antibody; RANTES; tumor necrosis factor alpha; virus antibody; animal experiment; animal model; article; blood sampling; controlled study; cytokine responsive element; disease severity; drug effect; drug inhibition; female; immune response; inoculation; lung lavage; mouse; nonhuman; pathogenesis; Respiratory syncytial pneumovirus; virus infection; virus replication; animal; Bagg albino mouse; biosynthesis; blood; disease model; immunology; methodology; physiology; virology; virus culture; Mus; Respiratory syncytial virus; Rice stripe virus; Animals; Antibodies, Monoclonal; Antibodies, Viral; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Plaque Assay; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Virus Replication
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178240
• Institution: National University of Singapore

10.1186/1743-422X-4-109