Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction

10.1186/1742-4690-2-23

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Main Authors:	Grainger, D.J, Lever, A.M.L
Other Authors:	MEDICINE
Format:	Article
Published:	BMC 2020
Subjects:	chemokine chemokine receptor antagonist chemokine receptor CCR5 chemokine receptor CXCR4 glycoprotein gp 120 ligand peptide 3 unclassified drug peptide virus receptor article chemotaxis drug mechanism human human cell Human immunodeficiency virus infection immunofluorescence in vitro study inhibition kinetics leukemia cell line protein protein interaction receptor binding signal transduction cell line drug effect Human immunodeficiency virus 1 macrophage metabolism pathogenicity synthesis virology Cell Line Chemokines Chemotaxis HIV Envelope Protein gp120 HIV-1 Humans Jurkat Cells Macrophages Peptides Receptors, CCR5 Receptors, HIV Signal Transduction
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178367
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1783672024-04-24T05:50:22Z Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction Grainger, D.J Lever, A.M.L MEDICINE chemokine chemokine receptor antagonist chemokine receptor CCR5 chemokine receptor CXCR4 glycoprotein gp 120 ligand peptide 3 unclassified drug chemokine chemokine receptor CCR5 glycoprotein gp 120 peptide virus receptor article chemotaxis drug mechanism human human cell Human immunodeficiency virus infection immunofluorescence in vitro study inhibition kinetics leukemia cell line protein protein interaction receptor binding signal transduction cell line drug effect Human immunodeficiency virus 1 macrophage metabolism pathogenicity signal transduction synthesis virology Cell Line Chemokines Chemotaxis HIV Envelope Protein gp120 HIV-1 Humans Jurkat Cells Macrophages Peptides Receptors, CCR5 Receptors, HIV Signal Transduction 10.1186/1742-4690-2-23 Retrovirology 2 2020-10-20T09:33:38Z 2020-10-20T09:33:38Z 2005 Article Grainger, D.J, Lever, A.M.L (2005). Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction. Retrovirology 2. ScholarBank@NUS Repository. https://doi.org/10.1186/1742-4690-2-23 1742-4690 https://scholarbank.nus.edu.sg/handle/10635/178367 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ BMC Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	chemokine chemokine receptor antagonist chemokine receptor CCR5 chemokine receptor CXCR4 glycoprotein gp 120 ligand peptide 3 unclassified drug chemokine chemokine receptor CCR5 glycoprotein gp 120 peptide virus receptor article chemotaxis drug mechanism human human cell Human immunodeficiency virus infection immunofluorescence in vitro study inhibition kinetics leukemia cell line protein protein interaction receptor binding signal transduction cell line drug effect Human immunodeficiency virus 1 macrophage metabolism pathogenicity signal transduction synthesis virology Cell Line Chemokines Chemotaxis HIV Envelope Protein gp120 HIV-1 Humans Jurkat Cells Macrophages Peptides Receptors, CCR5 Receptors, HIV Signal Transduction
spellingShingle	chemokine chemokine receptor antagonist chemokine receptor CCR5 chemokine receptor CXCR4 glycoprotein gp 120 ligand peptide 3 unclassified drug chemokine chemokine receptor CCR5 glycoprotein gp 120 peptide virus receptor article chemotaxis drug mechanism human human cell Human immunodeficiency virus infection immunofluorescence in vitro study inhibition kinetics leukemia cell line protein protein interaction receptor binding signal transduction cell line drug effect Human immunodeficiency virus 1 macrophage metabolism pathogenicity signal transduction synthesis virology Cell Line Chemokines Chemotaxis HIV Envelope Protein gp120 HIV-1 Humans Jurkat Cells Macrophages Peptides Receptors, CCR5 Receptors, HIV Signal Transduction Grainger, D.J Lever, A.M.L Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
description	10.1186/1742-4690-2-23
author2	MEDICINE
author_facet	MEDICINE Grainger, D.J Lever, A.M.L
format	Article
author	Grainger, D.J Lever, A.M.L
author_sort	Grainger, D.J
title	Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
title_short	Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
title_full	Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
title_fullStr	Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
title_full_unstemmed	Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
title_sort	blockade of chemokine-induced signalling inhibits ccr5-dependent hiv infection in vitro without blocking gp120/ccr5 interaction
publisher	BMC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178367
_version_	1800914493416407040

Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction

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