PRMT5-mediated regulation of developmental myelination

• Main Authors: Scaglione, A, Patzig, J, Liang, J, Frawley, R, Bok, J, Mela, A, Yattah, C, Zhang, J, Teo, S.X, Zhou, T, Chen, S, Bernstein, E, Canoll, P, Guccione, E, Casaccia, P
• Other Authors: BIOCHEMISTRY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: arginine; butyrolactone 3; gsk 591; histone deacetylase inhibitor; histone methyltransferase; lysine; nu 9056; PRMT5 protein; protein p53; unclassified drug; histone; Prmt5 protein, mouse; protein arginine methyltransferase; ablation; brucellosis; cell; inhibition; inhibitor; methylation; model validation; nervous system; protein; animal cell; animal experiment; Article; cell proliferation; controlled study; CRISPR-CAS9 system; histone acetylation; histone methylation; mouse; myelination; nonhuman; oligodendrocyte culture; oligodendrocyte precursor cell; animal; C57BL mouse; cell culture; cell differentiation; cell line; cell survival; CRISPR Cas system; cytology; gene expression profiling; genetics; HEK293 cell line; human; knockout mouse; metabolism; myelin sheath; oligodendroglia; stem cell; Mus; Animals; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; CRISPR-Cas Systems; Gene Expression Profiling; HEK293 Cells; Histones; Humans; Methylation; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Oligodendroglia; Protein-Arginine N-Methyltransferases; Stem Cells
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178404
• Institution: National University of Singapore

10.1038/s41467-018-04863-9