Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

• Main Authors: Dong, L.-F, Kovarova, J, Bajzikova, M
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: mitochondrial DNA; red fluorescent protein; animal cell; Article; C57BL/6N mouse; cancer cell; carcinogenic activity; cell respiration; chromatin immunoprecipitation; confocal microscopy; DNA transfer; gel electrophoresis; heteroplasmy; melanoma B16; melanoma cell; mitochondrial respiration; mouse; native blue gel electrophoresis; nonhuman; oxidative phosphorylation; polymerase chain reaction; animal; C57BL mouse; disease model; genetics; horizontal gene transfer; melanoma; pathology; tumor cell line; Animals; Cell Line, Tumor; Cell Respiration; Disease Models, Animal; DNA, Mitochondrial; Gene Transfer, Horizontal; Melanoma; Mice, Inbred C57BL
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178700
• Institution: National University of Singapore

10.7554/eLife.22187