JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia

• Main Authors: Mansour, M.R, He, S, Li, Z, Lobbardi, R, Abraham, B.J, Hug, C, Rahman, S, Leon, T.E, Kuang, Y.-Y, Zimmerman, M.W, Blonquist, T, Gjini, E, Gutierrez, A, Tang, Q, Garcia Perez, L, Pike Overzet, K, Anders, L, Berezovskaya, A, Zhou, Y, Zon, L.I, Neuberg, D, Fielding, A.K, Staal, F.J.T, Langenau, D.M, Sanda, T, Young, R.A, Look, A.T
• Other Authors: MEDICINE
• Format: Article
• Published: Rockefeller University Press 2020
• Subjects: basic leucine zipper transcription factor; caspase 3; ccnd2 protein; dexamethasone; doxycycline; glucocorticoid; jdp2 protein; microRNA 17 92; Myc protein; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1; Notch1 receptor; protein; protein kinase B; protein kinase Pim 1; protein mcl 1; protein Myb; RAG2 protein; short hairpin RNA; steroid; transcription factor RUNX2; unclassified drug; zinc finger E box binding homeobox 2; JDP2 protein, human; MCL1 protein, human; protein binding; repressor protein; zebrafish protein; acute lymphoblastic leukemia; animal experiment; animal model; apoptosis; Article; cancer survival; cell survival; controlled study; disease association; genetic association; human; human tissue; in vivo study; nonhuman; oncogene; priority journal; protein expression; regulatory mechanism; signal transduction; thymocyte; transgenic zebrafish; upregulation; animal; cancer transplantation; cell proliferation; disease model; DNA responsive element; drug effect; enhancer region; gene expression regulation; genetics; infant; metabolism; mouse; nucleotide sequence; pathology; preschool child; treatment outcome; zebra fish; Animals; Apoptosis; Base Sequence; Cell Proliferation; Cell Survival; Child, Preschool; Dexamethasone; Disease Models, Animal; Enhancer Elements, Genetic; Gene Expression Regulation, Leukemic; Glucocorticoids; Humans; Infant; Mice; Mutagenesis, Insertional; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation; Oncogenes; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Proto-Oncogene Proteins c-myc; Repressor Proteins; Response Elements; Thymocytes; Treatment Outcome; Zebrafish; Zebrafish Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179029
• Institution: National University of Singapore

10.1084/jem.20170484