The impact of hypoglycaemia awareness status on regional brain responses to acute hypoglycaemia in men with type 1 diabetes

• Main Authors: Dunn, J.T, Choudhary, P, Teh, M.M, Macdonald, I, Hunt, K.F, Marsden, P.K, Amiel, S.A
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Springer Verlag 2020
• Subjects: catecholamine derivative; epinephrine; glucose; growth hormone; hemoglobin A1c; insulin; neutral insulin; noradrenalin; oxygen 15; sterile water; acute disease; adrenalin blood level; adult; amygdala; angular gyrus; anterior cingulate; Article; awareness; blood biochemistry; body mass; brain blood flow; brain perfusion; brain region; cerebellum vermis; cingulate gyrus; clinical article; continuous infusion; diabetes control; disease duration; disease severity; dorsolateral prefrontal cortex; functional magnetic resonance imaging; functional neuroimaging; fusiform gyrus; globus pallidus; glucose blood level; glucose infusion; growth hormone blood level; hemoglobin blood level; human; hypoglycemia; image analysis; image processing; inferior temporal gyrus; insula; insulin blood level; insulin dependent diabetes mellitus; insulin treatment; lateral orbitofrontal cortex; lingual gyrus; male; medial frontal cortex; medial orbitofrontal cortex; middle temporal gyrus; morning dosage; noradrenalin blood level; operculum (brain); parahippocampal gyrus; positron emission tomography-computed tomography; postcentral gyrus; posterior parietal cortex; precuneus; primary motor cortex; priority journal; superior temporal gyrus; supramarginal gyrus; thalamus; white matter; blood; brain; diagnostic imaging; metabolism; middle aged; neuroimaging; pathophysiology; positron emission tomography; young adult; Adult; Awareness; Blood Glucose; Body Mass Index; Brain; Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Male; Middle Aged; Neuroimaging; Positron-Emission Tomography; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179030
• Institution: National University of Singapore

10.1007/s00125-018-4622-2