A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre-and post-chemotherapy

• Main Authors: Noorani, A, Bornschein, J, Lynch, A.G, Secrier, M, Achilleos, A, Eldridge, M, Bower, L, Weaver, J.M.J, Crawte, J, Ong, C.-A, Shannon, N, MacRae, S, Grehan, N, Nutzinger, B, O'Donovan, M, Hardwick, R, Tavaré, S, Fitzgerald, R.C
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Cold Spring Harbor Laboratory Press 2020
• Subjects: trinucleotide; antineoplastic agent; tumor protein; adult; aged; Article; cancer chemotherapy; cancer staging; cohort analysis; comparative study; controlled clinical trial; controlled study; endoreduplication; esophageal adenocarcinoma; female; gene dosage; gene mutation; human; major clinical study; male; priority journal; prospective study; quality control; whole genome sequencing; adenocarcinoma; biology; cell transformation; copy number variation; esophagus; esophagus tumor; gene expression profiling; gene expression regulation; genetics; high throughput sequencing; human genome; metabolism; middle aged; mutation rate; neoadjuvant therapy; pathology; point mutation; procedures; single nucleotide polymorphism; time factor; Adenocarcinoma; Aged; Antineoplastic Agents; Cell Transformation, Neoplastic; Computational Biology; DNA Copy Number Variations; Esophageal Neoplasms; Esophagus; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Mutation Rate; Neoadjuvant Therapy; Neoplasm Proteins; Point Mutation; Polymorphism, Single Nucleotide; Prospective Studies; Time Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179199
• Institution: National University of Singapore

10.1101/gr.214296.116